Organic Chemistry
有机化学研究碳化合物的结构、性质、合成和反应。课程涵盖烷烃、烯烃、炔烃、芳香烃、卤代烃、醇酚醚、醛酮、羧酸及其衍生物、含氮化合物等各类有机化合物的命名、结构与反应机理。重点讲解亲电加成、亲核取代、消除反应、氧化还原等基本反应类型,以及立体化学、有机波谱分析和有机合成设计等内容。
Organic Chemistry studies the structure, properties, synthesis, and reactions of carbon compounds. The course covers nomenclature, structure, and reaction mechanisms of alkanes, alkenes, alkynes, aromatics, alkyl halides, alcohols, phenols, ethers, aldehydes, ketones, carboxylic acids and derivatives, and nitrogen compounds. Key topics include electrophilic addition, nucleophilic substitution, elimination, redox reactions, stereochemistry, spectroscopy, and synthesis design.
选定一个目标有机分子(如药物中间体或天然产物),设计至少两条合成路线,比较其原子经济性和步骤经济性,阐明关键反应的机理,并讨论立体化学问题。
Choose a target organic molecule (e.g., drug intermediate or natural product), design at least two synthesis routes, compare atom and step economy, elucidate key reaction mechanisms, and discuss stereochemical issues.