Metabolic Biochemistry
本课程系统讲授生物体内物质代谢和能量转换的基本规律。内容涵盖糖代谢（糖酵解、三羧酸循环、磷酸戊糖途径、糖异生、糖原代谢）、脂代谢（脂肪酸氧化、酮体生成、脂类合成）、氨基酸代谢（脱氨基、转氨基、尿素循环）、核苷酸代谢及代谢调控网络。重点理解各代谢途径的关键酶、调控机制及途径间的相互联系，掌握代谢紊乱与疾病的关系，为后续专业学习和研究奠定理论基础。
This course systematically covers the fundamental principles of substance metabolism and energy conversion in living organisms. Topics include carbohydrate metabolism (glycolysis, TCA cycle, pentose phosphate pathway, gluconeogenesis, glycogen metabolism), lipid metabolism (fatty acid oxidation, ketogenesis, lipid synthesis), amino acid metabolism (deamination, transamination, urea cycle), nucleotide metabolism, and metabolic regulatory networks. Emphasis on key enzymes, regulatory mechanisms, and pathway interconnections.
选择一个代谢途径（如糖酵解或三羧酸循环），分析其调控机制，设计实验测定关键酶（如己糖激酶或柠檬酸合酶）的活性与动力学参数。
Select a metabolic pathway (e.g., glycolysis or TCA cycle), analyze its regulatory mechanisms, design experiments to determine activity and kinetic parameters of key enzymes (e.g., hexokinase or citrate synthase).