Molecular Biology
本课程从分子水平研究基因的结构、表达与调控机制。内容涵盖DNA复制、转录、翻译的分子机制，基因表达的转录水平和转录后水平调控，RNA的加工与功能，蛋白质的合成、修饰与降解，以及信号转导通路。重点介绍原核生物和真核生物基因表达调控的差异，染色质结构与表观遗传调控，以及分子生物学常用研究技术如PCR、分子克隆、核酸杂交、测序技术等，为深入理解生命活动的分子机制奠定基础。
This course studies gene structure, expression, and regulatory mechanisms at the molecular level. Topics include molecular mechanisms of DNA replication, transcription, and translation; transcriptional and post-transcriptional gene regulation; RNA processing and function; protein synthesis, modification, and degradation; and signal transduction pathways. Emphasis on differences between prokaryotic and eukaryotic gene regulation, chromatin structure and epigenetic regulation, and common molecular biology techniques such as PCR, molecular cloning, nucleic acid hybridization, and sequencing.
选择一个蛋白质或核酸分子，使用生物信息学工具（如AlphaFold、PyMOL）预测其三维结构，分析结构与功能的关系，撰写研究报告。
Select a protein or nucleic acid molecule, use bioinformatics tools (e.g., AlphaFold, PyMOL) to predict its 3D structure, analyze structure-function relationship, write research report.