Organic Chemistry
本课程系统讲授碳化合物的结构、性质、反应及其机理。内容涵盖烷烃、烯烃、炔烃、芳香烃、卤代烃、醇酚醚、醛酮醌、羧酸及其衍生物、胺类等主要有机化合物的命名、结构与反应。重点讲解取代反应、消除反应、加成反应、重排反应等基本反应类型及其机理,介绍立体化学、波谱分析等重要概念,为生物化学专业学习奠定有机化学基础。
This course systematically covers the structure, properties, reactions, and mechanisms of carbon compounds. Topics include alkanes, alkenes, alkynes, aromatic hydrocarbons, alkyl halides, alcohols, phenols, ethers, aldehydes, ketones, quinones, carboxylic acids and derivatives, and amines. Emphasis is placed on substitution, elimination, addition, and rearrangement reaction mechanisms, stereochemistry, and spectroscopic analysis, providing essential organic chemistry foundations for biochemistry studies.
学生需设计阿司匹林(乙酰水杨酸)的多步合成路线,从基础原料出发,选择合适的反应条件和试剂,写出每一步的反应方程式和机理。报告需包含合成路线设计、反应机理详解、产率估算、纯化方案及安全性评估,理解有机合成在药物开发中的应用。
Students design a multi-step synthesis route for aspirin (acetylsalicylic acid) starting from basic raw materials, selecting appropriate reaction conditions and reagents, and writing reaction equations and mechanisms for each step. The report includes synthesis route design, detailed reaction mechanisms, yield estimation, purification protocols, and safety assessment, illustrating organic synthesis applications in drug development.