Physical Chemistry
本课程运用物理学原理和数学方法研究化学系统的基本规律。主要内容包括热力学三大定律、化学平衡、相平衡、电化学、化学动力学、表面化学和胶体化学等。重点培养学生从微观和宏观两个层面理解化学现象的能力，掌握热力学函数计算、反应速率理论和电化学原理，为理解生物大分子的结构稳定性、酶促反应动力学等生物化学问题提供理论基础。
This course applies physical principles and mathematical methods to study chemical systems. Topics include the three laws of thermodynamics, chemical equilibrium, phase equilibrium, electrochemistry, chemical kinetics, surface chemistry, and colloid chemistry. Students develop understanding of chemical phenomena at both microscopic and macroscopic levels, mastering thermodynamic function calculations, reaction rate theory, and electrochemical principles essential for understanding biomolecular stability and enzyme kinetics.
学生需设计实验测定某一酶促反应的米氏常数Km和最大反应速率Vmax，选择合适的底物浓度梯度和检测方法，运用Lineweaver-Burk双倒数作图法进行数据处理。报告需包含实验原理、数据记录表、动力学参数计算、抑制剂类型判断及误差分析，深入理解酶促反应的动力学特性。
Students design an experiment to determine the Michaelis constant Km and maximum reaction rate Vmax of an enzyme-catalyzed reaction, selecting appropriate substrate concentration gradients and detection methods, and processing data using Lineweaver-Burk double-reciprocal plots. The report includes experimental principles, data tables, kinetic parameter calculations, inhibitor type determination, and error analysis, deepening understanding of enzyme reaction kinetics.