遗传学

课程介绍 Course Introduction

学分：3 | 先修课：普通生物学 | 学期：第三学期

本课程系统阐述遗传学的基本原理和方法，内容包括孟德尔遗传定律、染色体遗传、连锁与交换、基因定位、基因突变、染色体畸变、细胞质遗传、数量遗传、群体遗传以及分子遗传学基础。课程结合人类遗传病案例进行讲解，培养学生运用遗传学原理分析和解决生物医学问题的能力。

This course systematically presents fundamental principles and methods of genetics. Topics include Mendelian inheritance, chromosomal genetics, linkage and crossing over, gene mapping, gene mutation, chromosomal aberrations, cytoplasmic inheritance, quantitative genetics, population genetics, and molecular genetics basics. The course uses human genetic disease cases for instruction.

大作业 Final Project

作业标题：人类遗传病系谱分析与遗传咨询报告

学生选取一种单基因遗传病（如白化病、红绿色盲、血友病等），收集该疾病的系谱图案例，进行遗传方式分析，计算再发风险，并撰写一份遗传咨询报告。报告需包括疾病概述、系谱图绘制、遗传方式判断、风险评估和咨询建议，培养系谱分析和遗传咨询能力。

Students select a monogenic genetic disease, collect pedigree cases, analyze inheritance patterns, calculate recurrence risks, and write a genetic counseling report. The report includes disease overview, pedigree drawing, inheritance pattern determination, risk assessment, and counseling recommendations, developing pedigree analysis and genetic counseling skills.