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有机化学

Organic Chemistry

课程介绍 Course Introduction

学分:4 | 先修课:普通化学 | 学期:第二学期

本课程系统介绍有机化学的基本理论和方法,包括有机化合物的结构、命名、性质、合成及反应机理。内容涵盖烷烃、烯烃、炔烃、芳香烃、卤代烃、醇酚醚、醛酮醌、羧酸及其衍生物、胺类化合物、杂环化合物以及生物分子(糖类、脂类、氨基酸、蛋白质、核酸)。课程注重有机化学与生物医学的联系。

This course systematically introduces basic theories and methods of organic chemistry, including structure, nomenclature, properties, synthesis, and reaction mechanisms of organic compounds. Topics cover alkanes, alkenes, alkynes, aromatic hydrocarbons, alkyl halides, alcohols, phenols, ethers, aldehydes, ketones, carboxylic acids and derivatives, amines, heterocyclic compounds, and biomolecules. The course emphasizes connections to biomedicine.

大作业 Final Project

作业标题:阿司匹林的合成与纯度鉴定

学生以水杨酸和乙酸酐为原料,通过酯化反应合成阿司匹林粗品,经重结晶提纯后,采用熔点测定法和薄层层析法进行纯度鉴定。实验需记录反应条件、产率计算、纯度分析结果,并讨论影响产率和纯度的因素,培养有机合成和产物鉴定的实验技能。

Students synthesize crude aspirin from salicylic acid and acetic anhydride via esterification, purify it by recrystallization, and identify purity using melting point determination and thin layer chromatography. The experiment requires recording reaction conditions, calculating yield, analyzing purity, and discussing factors affecting yield and purity, developing organic synthesis and product identification skills.